You should try and take all your doses correctly. The best response to anti-HIV therapy is seen in people who had 100% adherence to their treatment. Levels of adherence of less than 95% have been associated with poor suppression of HIV viral load, rebound in viral load, and either poor CD4 cell gains or falls in CD4 cell count.

If you are taking your treatment once a day, 95% adherence means missing, or incorrectly taking, only one dose a month.

If you are taking your treatment twice a day, 95% adherence means missing, or incorrectly taking, only three doses a month.

If you are taking your medication three times a day, 95% adherence means missing, or incorrectly taking, only four doses a month.

Adherence at this level can be very hard, and is much higher than the level needed for other medication. Nevertheless, try to take all your doses. Remember, any fall in the level of drug levels in your blood will give an opportunity for strains of HIV to develop which drugs don’t work against.